Category: xgliz

3 people to watch in neuroscience in 2016

first_img @sxbegle Charlotte Chua for STAT [email protected] As the year winds down, STAT reporters are taking a look at the stories they’re most eager to track in 2016. We’ll be running these daily through Dec. 31. Look for more New Year’s predictions here. President Obama’s BRAIN Initiative is the biggest thing in brain science, and as such it’s what we at STAT have got our eyes on for neuroscience advances in the year ahead.The initiative awarded its first $46 million in grants in September 2014 and the next $38 million a year later. Although the projects are funded for three years, scientists have already reported interim findings, such as how they used designer molecules to turn mouse neurons on and off. Here are three groups to watch in 2016:D. Kacy Cullen, University of Pennsylvania Cullen and his colleagues are in hot pursuit of “neurosurgical reconstruction.” The idea is to rebuild brain circuitry with what they call “living electrodes”: tiny, biodegradable tubes packed with axons, the long filaments that carry signals out of one neuron and into another. The tubes are inserted into a brain, they melt away, and the axons form functional circuits with the rest of the cortex.advertisement It’s already worked in rat brains, the scientists reported in November, so 2016 could bring more progress toward rebuilding brains damaged by trauma and degenerative diseases such as Parkinson’s.Julie Ann Brefczynski-Lewis, West Virginia UniversityCurrent neuroimaging technology works only when someone is basically immobilized. As a result, it’s been challenging to study brain activity when people do what they do during their waking hours. Brefczynski-Lewis’s lab is working toward the first mobile brain imager so scientists can peer at brain activity while, for instance, someone is walking, playing a piano, meditating, or socializing.advertisement By Sharon Begley Dec. 23, 2015 Reprints About the Author Reprintscenter_img In the Lab3 people to watch in neuroscience in 2016 That device, called the AM-PET Helmet, could not only help crack the mysteries of the human brain, it could also potentially treat neurologic conditions, such as dementia, stroke, traumatic brain injury, and depression. The researchers have already made progress on the device, such as figuring out the best way to arrange detecters around the head.Nicholas Melosh, Stanford University A chemist and materials scientist, Melosh is emblematic of the BRAIN Initiative’s efforts to bring new perspectives and strengths to neuroscience. He and his team plan to make self-propelled electrodes to better study both basic brain processes as well as neurological diseases and brain injuries.Stiff push-in electrodes currently in use are hard to deploy to fine targets. Instead, Melosh envisions thousands of ultrathin flexible electrodes in a single implanted device that “will ‘pull’ themselves from the front” using a sort of front-wheel-drive technology, the scientists wrote in their proposal. They’re also looking for ways of steering the electrodes so “they can extend throughout the brain in three dimensions and plant themselves next to individual neurons.”That could help basic research, letting scientists measure activity in more precisely targeted brain regions of lab animals, and also possibly help patients, using electrodes to stimulate certain neurons as a way to treat memory problems and possibly even comas. Sharon Begley Senior Writer, Science and Discovery (1956-2021) Sharon covered science and discovery. Tags brainneuroscienceThree to watchlast_img read more

Seeking reform, a neuroscientist argues against ‘sexist’ beliefs that keep research focused on male animals

first_img But some are concerned that the NIH’s mandate and even experiments that pay more attention to female models might reinforce the idea sex is the only way to explain biological differences.“It’s just important for us to not repeat the idea that sex is the ultimate variable that’s going to explain everything,” said Rebecca Jordan-Young, a sociomedical scientist at Barnard College. “The way sex actually relates to multiple other variables across animals is not the same [as in humans].”With the Ambien example, for instance, some recent research has suggested that it may be body size and not necessarily sex that’s behind why some people may need a different dose of the drug.Shansky agreed that sex isn’t the only variable. Even the strain of rat that a researcher uses can influence the results. “I do not think ‘rat strain as a biological variable’ is something NIH will add soon, but those are things worth thinking about when scientists choose experimental design,” Shansky said.Because these basic biomedical studies do carry weight in the real-world, she said, it’s ultimately important to be careful about variables and pay attention to any differences that they bring.“What we hope is that the things that work their way out into the actual world and into translational-level studies are the things that are really robust effects and that shouldn’t necessarily be so sensitive to things like sex,” Shansky said. “If it’s going to work in a human, maybe it should work in more than one strain of rat.” Shraddha Chakradhar Leave this field empty if you’re human: Shansky also suggests instead that researchers, especially in neuroscience, start with an equal number of male and female animals and conduct their experiments without the assumption of sex-based differences. If differences emerge that suggest that sex could be a variable, then the scientists could follow up with larger studies examining each sex more closely.“I think the suggestion that one needs to have an equal number of females and males and do statistical analysis to find outliers is a good one,” said Catherine Dulac, a Howard Hughes Medical Institute investigator and neurobiologist at Harvard University. “People have to get used to having sex as a variable — for many studies I bet it won’t matter and for some I bet it will.”Dulac also said that the NIH’s mandate may not be going far enough, since there is no requirement to use female animals — it only asks researchers to account for sex in some way.“The problem is that [researchers] are going to think about it for 30 seconds to say why they can’t use female mice,” Dulac said. “You hope that they have that tinge of guilt [from not using female mice] because the situation is really becoming unbearable.”Another way forward may be to focus on the next generation of scientists. “There’s shaming, and there’s training,” Dulac said. “I think training is the way to go forward.”Nicole Woitowich, associate director for the Women’s Health Research Institute at Northwestern University, agreed, saying there may be resistance from current scientists.“With folks who are set in their ways, I just don’t know that they are going to change their practices,” she said. “Training is our best hope for changing our attitudes towards sex and gender-inclusive research.” @scchak Please enter a valid email address. Trending Now: Her research also found that the perception that variability only exists in female mice may not actually be rooted in fact. A 2014 meta-analysis of some 300 mouse studies found that physiological, behavioral, and other biological measures in male and female subjects did not vary much regardless of the estrous cycle. Another such analysis from 2016 looked at rat studies and found similar results.“If you think that females are more variable than males, that is not based in reality,” Shansky told STAT. “That is based on your perception of what you think ovarian hormones do to a female animal, and that’s sexist.”In a statement Thursday, Chyren Hunter of the NIH’s Office of Research on Women’s Health refuted the validity of the idea that female hormones are more variable than male hormones. “The belief that non-human female mammals are intrinsically more variable than males and therefore should be excluded from routine inclusion in research protocols is without foundation and has been refuted in peer-reviewed publications,” Hunter told STAT.In fact, at least one study found that depending on whether animals were housed alone or in groups, males — because of dominance-induced changes — could actually have high variability in testosterone, a variability that Shansky said is not taken into account on a regular basis.Even cortisol, the so-called stress hormone, fluctuates throughout the day. “No one has said you have to do two experiments twice a day, once in the daytime and once in the nighttime, for male studies of drug efficacy,” she said.And even though the NIH’s 2016 mandate was intended to correct for some of this one-sidedness in research, Shansky said that may not be enough. The mandate doesn’t explicitly say how scientists ought to go about including both male and female animals, for instance, and Shansky writes in her paper that this lack of direction means researchers often still go to male animal models first and then try to replicate the findings in the female models. Studying sex differences will improve health for women and men Starting in 2016, the National Institutes of Health mandated that researchers applying for grants factor sex as a variable into experiment design and data analyses. But one neurobiologist argues that outdated gender stereotypes, many of which are not evidence-based, are still finding their way into scientific experiments.In a perspective published Thursday in Science, Northeastern University neurobiologist Rebecca Shansky said that one of the biggest misconceptions among her colleagues and many male and female scientists is that female hormones — and the estrous cycle in mice, which corresponds to the menstrual cycle in women — are “messy” and complicate matters for research.“It seems that we are applying all of these higher standards for rigor to female animals that we haven’t had for male animals, and it’s all essentially based around this idea of ovarian hormones, and that to me just seems really wrong.”advertisement Ambien is an example frequently cited by proponents of sex parity in research. The insomnia drug was approved in 1992, a year before the Food and Drug Administration lifted a ban on women’s routine participation in clinical trials. After reports of dangerous side effects, including women being involved in car crashes due to what’s known as “sleep driving,” the FDA in 2013 required the manufacturer to halve the recommended standard dose for women. Women seem to metabolize the drug more slowly, the FDA said, and that caused the effects of Ambien to stick around until the next morning.And that’s just the most famous example. “Immunology research has discovered that there are differences in how men and women respond to vaccines, and it’s also well-known that symptoms of heart attacks are different,” said Margaret McCarthy, a neuroscientist and pharmacologist at the University of Maryland School of Medicine. “Pretty much at this point, there isn’t a common organ that men and women share that doesn’t have differences.”But beyond the regular inclusion of women in clinical trials, even the inclusion of female animals in research continues to be a problem. McCarthy, who helps review intramural grant applications for the NIH, said one of the common themes is the failure to incorporate sex as a biological variable into applications.“The message is really not getting out nearly as well as it should,” McCarthy said.And so Shansky wanted to investigate the origins of what she calls a “dogma” about female hormones being inherently problematic for clean, uncomplicated research.Her research took her to Victorian times, when the idea of women being unstable and at the whim of their emotions had a stronghold in the scientific community.“This perception that women are emotional and hormonal was sort of a deliberate narrative, constructed in the Victorian era by biologists and psychologists to essentially preserve the patriarchy,” Shansky said in the conference call. As a result, basic research — unless it sex-specific research — has largely used only male animal models. Results from these studies form the foundation of more rigorous clinical trials, and ultimately lead to drugs that are used by both men and women.“I would hope that if a researcher considers their research to be clinically relevant, then they would want it to be clinically relevant for everyone and not just men,” Shanksy said in a conference call this week with reporters.advertisement Newsletters Sign up for Daily Recap A roundup of STAT’s top stories of the day. Male doctors said my ‘female’ cancer was incurable. Then a woman took command and gave me hope center_img Privacy Policy Tags research Related: In the LabSeeking reform, a neuroscientist argues against ‘sexist’ beliefs that keep research focused on male animals [email protected] Related: Adobe Reporter, Morning Rounds Writer, Intern Coordinator Shraddha writes the Morning Rounds newsletter and covers health and medicine. By Shraddha Chakradhar May 30, 2019 Reprints About the Author Reprints Comparing the Covid-19 vaccines developed by Pfizer, Moderna, and Johnson & Johnson last_img read more

Camogie season gets down to business as final places up for grabs

first_img GAA Kelly and Farrell lead the way as St Joseph’s claim 2020 U-15 glory 2020 U-15 ‘B’ glory for Ballyroan-Abbey following six point win over Killeshin By Steven Miller – 14th September 2019 WhatsApp WhatsApp Home GAA Camogie Camogie season gets down to business as final places up for grabs GAACamogieSport Twitter GAA Pinterest Twitter Camogie season gets down to business as final places up for grabs GAA Previous articleZach and Geelong bounce back with Australian Rules Grand Final now just one game awayNext articleFr Paddy: Transform your difficulties and draw goodness from the negatives Steven Millerhttp://www.laoistoday.ieSteven Miller is owner and managing editor of From Laois, Steven studied Journalism in DCU and has 14 years experience in the media, almost 10 of those in an editorial role. Husband of Emily, father of William and Lillian, he’s happiest when he’s telling stories or kicking a point. RELATED ARTICLESMORE FROM AUTHOR Pinterest They beat their rivals by five points in the opening round before then seeing of St Brigid’s by three in their next championship outing and then having 13 points to spare over today’s opponents The Harps.As always the likes of Kirsten Keenan, the Fitzgerald sisters, the Burkes, Sara Cuddy, Maeve Collier and Niamh Dollard will be vital for Camross and they should have too much for a Harps team that failed to win any of their group games.Molly and Lucy O’Connor as well as Alice Walsh all tasted All Ireland minor glory with Laois this year and will be central for The Harps. But Camross will be favourites.Camross and Portlaoise to meet in junior finalOn a busy weekend of camogie fixtures, Camross and Portlaoise advanced to the final of the junior championship on Friday night when they got the better of Naomh Eamann and The Harps respectively.Camross struck late to deny Naomh Eamann and won on a scoreline of 3-4 to 3-2.Naomh Eamann, who are mostly made up of girls from Castletown and Slieve Bloom, led for most of the game but Camross stuck for the winning goal in injury time.In the other semi-final on Friday night, Portlaoise, in their first year of adult camogie, were too strong for The Harps’ second team and won 3-6 to no score.SEE ALSO – Check out all the LaoisToday camogie coverage here Facebook Here are all of Wednesday’s Laois GAA results O’Moore’s put their Laois camogie title on the line in the championship semi-final against St Brigid’s on Saturday Today is a big day for the Laois club camogie scene with the two championship semi-finals down for decision in Mountrath this evening as part of a double header.O’Moore’s v St Brigid’sIn Mountrath at 4pmThe first game sees county champions O’Moore’s take on St Brigid’s at 4pm.O’Moore’s are seeking a third title in four years having only won their first in 2013.It completes a busy week for a good chunk of the O’Moore’s team many of whom were part of the Sarsfields ladies football side that won the county final last Sunday.Captain of the Sarsfields side Rosemarie Bermingham is one of many county players in the O’Moore’s side and she’s joined by the likes of the McEvoy and Williams sisters, Mary Keating, Liadan C. Fennell and Amy Loughman who are all excellent players.O’Moore’s only narrowly got the better of St Brigid’s when the sides met in the group stages in July and it’s hard to see a massive amount separating the sides on this occasion either.St Brigid’s can call on the likes of Laura Dunne, Clodagh Tynan, Saragh Creagh, Jessie Quinlan, Roisin Kilmartin and Aisling O’Dea and they’ll be keen to upset the odds and book their county final place.The Harps v CamrossIn Mountrath at 6pmCamross arrive into the semi-final as the top-ranked team with three wins from three in the group stages and hell-bent on winning back the title they lost to O’Moore’s 12 months ago. Facebooklast_img read more

Portlaoise Hospital delivers two of Ireland’s first babies of 2021

first_imgHome News Community Portlaoise Hospital delivers two of Ireland’s first babies of 2021 NewsCommunity Two of the first babies to be born in Ireland in 2021 were delivered in the early hours of New Year’s Day in Portlaoise Hospital.The first, at just four minutes past midnight, is certainly close to being the newest member of 2021 in the entire country.Lily Bernadette Snell came into the world to the immense joy of Maggie Keatley and partner Frank Snell who both come from Kildare.A spokesperson for Portlaoise Hospital said: “Baby Lily Bernadette Snell came into the world at 4 minutes past midnight to the delight of Maggie Keatley and partner Frank Snell, from Kildare.“Congratulations to you all and best wishes.”In what was a much quieter New Year’s Day than ever for most of us, the staff in the maternity unit were very busy as another baby arrived a short few hours later.Laois parents Manda Byrne and Enda Gorman were celebrating as baby Jamie entered the world.Congratulations to all! Twitter Facebook Electric Picnic RELATED ARTICLESMORE FROM AUTHOR Twitter WhatsApp Electric Picnic organisers release statement following confirmation of new festival date SEE ALSO – Coronavirus: Four further deaths and 3,394 new cases – 104 of them in Laois Laois Councillor ‘amazed’ at Electric Picnic decision to apply for later date for 2021 festival WhatsAppcenter_img Pinterest Pinterest Electric Picnic Electric Picnic Facebook TAGSPortlaoise Hospital By Alan Hartnett – 3rd January 2021 Previous article2020 Remembered: Laois Garda saves person’s life at full flood in River BarrowNext articleDeaths in Laois – Sunday, January 3, 2021 Alan HartnettStradbally native Alan Hartnett is a graduate of Knockbeg College who has worked in the local and national media since 2008. Alan has a BA in Economics, Politics and Law and an MA in Journalism from DCU. His happiest moment was when Jody Dillon scored THAT goal in the Laois senior football final in 2016. Portlaoise Hospital delivers two of Ireland’s first babies of 2021 Electric Picnic apply to Laois County Council for new date for this year’s festivallast_img read more

Do You Know of the Bloody Purge in Pyongyang?

first_imgNews Do You Know of the Bloody Purge in Pyongyang? By Daily NK – 2005.02.09 12:03pm Entire border patrol unit in North Hamgyong Province placed into quarantine following “paratyphoid” outbreak SHARE RELATED ARTICLESMORE FROM AUTHOR There are signs that North Korea is running into serious difficulties with its corn harvest AvatarDaily NKQuestions or comments about this article? Contact us at [email protected] center_img Facebook Twitter News [imText1]In 1997, Pyongyang was swept by the bloody purge. It was a generational “clean up” which included execution of Suh Kwan Hee, the former secretary of Agriculture Department of the Labor Party, Pi Chang Lin, the former vise-president of Agriculture Science Institute, former secretary general of Gaesung City Party, and Suh Yoon Seok, former secretary general of Pyongyang City Party. November of the same year, the prevailing rumor was “the National Security Department got rid of the spies hired by Americans” across the nation. The full story is that Suh Kwan Hee opposed to the party’s agriculture policy and spoiled the nation’s entire agriculture and ultimately tried to starve the population to death. They “made” the evidence that Suh Kwan Hee had connections with South Koreans and accused him of being a spy. He was executed openly at the Bus rotary in the Road of Unification in Pyongyang city. Because of Suh Kwan Hee incident, Kim Man Keum, the former commissioner of the Agriculture Committee, was “re-killed.” Kim Man Keun was the one who guaranteed Suh’s political life. Kim had already died in 1984, whose body was buried at the Cemetery of Patriots, and his remains were taken out of his grave to be gunshot.1997 was the year three million peopled died of starvation. Dead bodies were lying everywhere that one had to walk over them. For Kim Jong Il, the food crisis was inexcusable unless it could be blamed on someone. For this reason, they made up the “American Spy Incident.” The most common accusation the North Korean government comes up with is either incident of “American spies” or “spies hired by South Korea.” “American Spy Incident.” However, how frequent it may be, once accused there is no way out of that bloody wave of sword. When Pi Chang Lin was executed, there were nineteen of them accused with him. They were all arrested and executed. The official crime the National Security Department sentenced Pi with was that he was “converted” when he was arrested while he was a North Korean spy in North Korea during the Korean War. The National Security Department publicly announced that Pi Chnag Lin was hired by Americans as a spy with an order to murder Kim Jong Il and got involved in the “Revolutionary Movement” after camouflaged as an escapee. The other nineteen accused included vice secretary of the Central Party, a number of secretary generals of different province parties, and other figures. With the special order from Kim Jong Il, the political secretary of the National Security Department at the time executed all of them in the firing ground of the National Security Department locate in Pyongyang city. Kim Jong Il Totalitarian Regime Made a System for Everyone to Accuse Each Other After a while, Suh Yoon Seok, the secretary general of the Pyongyang City Party at the time was arrested. Suh used to be chubby, so people of Pyongyang city used to call him “Suh Daegam” (call name such as “Don”). He was imprisoned in the Security Department’s detention camp accused of “unclear past.” While the entire region around Pyongyang was in deadly mood, Suh emaciated so much that he was left with only bones and skin. Secretary general of Pyongyang City Party is a well-respected position. Towards the end of the mass purge, as if worried that execution of Suh Yoon Seok is taking the wave of purge too far, Kim Jong Il called on Suh on day. When Kim Jong Il saw Suh barely alive, got angry at political secretary of the National Security Department and revoked him, “Who are you to kill this many people?” Baek Hak Lim, the political secretary of the National Security Department at the time, was an old man who did not do much more than merely holding the position. Few days later, Baek Hak Lim was executed, accused of a “anti-party, anti-revolutionary” and Kim Jong Il changed the name of “National Security Department” to “People’s Security Department,” saying that he is sick of hearing about the National Security Department. Here, we can have a glimpse at the cunning politics played by Kim Jong Il. Kim Jong Il proclaimed “I have no responsibility in economics”(Dec, 1996) afraid that he will be blamed for the millions starved to death. He blamed on Suh Kwan Hee and others for holding all the responsibility of the food crisis and made the city of Pyongyang shake in fear of death, then he blamed political secretary of the National Security Department to make sure people do not blame on himself. People living in that reality could not do much more than just grieve and question, “How can there be so many spies in such a small country? People’s lives are worth only lives of flies.” In North Korea, you can always become an “American spy” or a “spy hired by South Korea” if you do not obey Kim Jong Il. If you question about Kim Jong Il’s order, you can disappear accused as “anti-revolutionary.” Kim Jong il made a regime where people can only survive when they accuse each other and obey only Kim Jong Il. If you do not follow the system, you cannot survive. When would South Korean people really get to know about this “fact” about Kim Jong Il? Han Young Jin, North Korean defector reporter at The DailyNK, defected from Pyongyang in 2002. North Korea tries to accelerate building of walls and fences along border with China News News last_img read more

Price Won’t Seek House Majority Leader Spot

first_img ‘It’s Fractured’: Georgia Lt. Gov. Geoff Duncan On Healing Republican Party For Whom The Bell Rings Related Stories Share Legal Advocate Discusses Medical Abuse At Shut Down Georgia ICE Facility Add to My List In My List Georgia Republican Rep. Tom Price says he won’t be among those jockeying to replace outgoing Virginia Rep. Eric Cantor as House Majority Leader.After a stunning primary election defeat to Tea Party-backed candidate David Brat Tuesday, Cantor yesterday announced he’d be stepping down from the position in July, prompting a flurry of speculation as to who might replace him. Price was considered by many to be on the short list of contenders for the spot. In  a statement released Thursday, Price said while the encouragement has been “humbling,” he’d instead be focusing on the position of chairman of the House Budget Committee. Read the full statement below. “The encouragement I’ve received from colleagues over the past couple of days has been humbling. My position has always been that I”m ready to serve in whatever capacity might best help unify our team, promote our conservative principles and, above all, pursue positive solutions on behalf of our constituents. To that end, at this time, my focus is on the opportunity to serve as the next chairman of the House Budget Committee.”last_img read more

The real SVU: NYPD’s Special Victims Division gets a makeover

first_imgNYPD(NEW YORK) — The new NYPD Special Victims Division looks nothing like the grubby precinct on television.There is a brightly lit waiting area, comfortable seating and soothing paint color-s on the walls.Believing design makes a difference, the NYPD has given the division a makeover to encourage sex assault and rape victims to come forward.The new Special Victims Division center, located at 137 Centre Street, just across from the Manhattan DA’s office, is part of a “victim centered” approach meant to make the experience of talking to detectives less intimidating and more private. The SVD has been undergoing extensive reforms over the last 18 months, according to officials.“The significant facility improvements, increased staffing, enhanced training and new leadership within our Special Victims Division amplify our ability to respond effectively to survivors of all crimes, while continuing to conduct thorough and victim-centered investigations,” Police Commissioner James P. O’Neill said in a press release. “The NYPD remains deeply committed to ensuring survivors feel the safety and support needed to come forward, bravely share their experiences, and help the NYPD bring to justice those who have committed these horrific crimes.”The changes come after the city’s Department of Investigation found that SVD was understaffed and ill-equipped to deal with a massive caseload. In response, 35 detectives were added.Copyright © 2019, ABC Radio. All rights reserved.last_img read more

Director, Center for Climate Action and Sustainability : 3 year Administrative Faculty Position

first_imgThe primary task of the Director will be to collaborativelyenvision, create and lead the Center for Climate Actionand Sustainability, with the support of an advisory board, as a hubfor students, staff, faculty and community members who areinterested in climate action and sustainability. The Director willcoordinate with other Public Service Centers such as the Center forEntrepreneurial Leadership and Transformational Change (CELTC) andthe Center for Community Based Learning and Action (CCBLA) to builda robust set of internship opportunities with community partners.The Climate Center will serve as a resource for both campus andcommunity, organizing events and curricularofferings.    In addition, the Director may teach courses and modules ontopics related to their training and background. These may also bedeveloped as certificate programs for matriculatedand non-matriculated students, either for-credit ornot-for-credit, and may be offered online, in hybrid format or oncampus. The Director will provide support to students, staff andfaculty involved with co-curricular learning opportunities thatdevelop capacities of students to become leaders in communityorganizing, applied climate science, energysystems, sustainability, climate justice, food systems,communication, or any number of related fields. Such areas mayinclude Evergreen’s organic farm, theOlympia EcoDistrict project, partnering with localindustries working on climate solutions, among otherinitiatives.  This may include sponsoring contracts andinternships for students studying in climate-relatedfields.  The Director will also assist with a variety of curriculartasks. They will coordinate the design and deliveryof climate action and sustainability curricular andco-curricular offerings associated with the Center. TheDirector also will support faculty-developed climateaction and sustainability academic and co-curricular offeringsassociated with the Center. Given Evergreen’sinterdisciplinary structure, this may include faculty from thesciences, social sciences, arts, media, food and agriculture, andrelated curricular areas.   The Evergreen State College is establishing a new Center forClimate Action and Sustainability (CCAS) to help aligncurriculum, student interest and communitypartnerships.  The CCAS furthers Evergreen’s missionby supporting students and the broader community in developingjustice-oriented, science-based, and equitable solutions to theclimate crisis. This center will augment our current capacityto provide hands-on, applied, interdisciplinary learningopportunities for students. We invite a creative leader to build aClimate Center that supports students and facultyin climate-related sciences, climate justice, climatesolutions and community action.  In collaboration with theProvost’s team, the Director will provide leadership for the Centerby supporting the development of curriculum, including internshipsand capstone experiences. Additionally, the Director will developand teach certificate programs and other curricular elements thatsupport climate action and sustainability. This is anadministrative faculty position that reports to the Vice Provostfor Academic Operations.  The Director will also provide administrative leadership to theCenter. In collaboration with the Provost’s team, they will preparea business plan, yearly action plan and associated budget for theCenter.  This will include monitoring spending under theinitiative and working with the Vice President for Advancement andAcademic Budget Coordinator to prepare a quarterly report on howproject funds are allocated.  The Director will alsowork with the Provost and Advancement to develop a long-termproject funding strategy and assist with fundraising as needed.They will develop measures for assessing the success of the Centerand assist in implementing an assessment process.  TheDirector may supervise a program assistant providing administrativeand program support for the Center and oversee the work ofstudent workers and interns supporting specificprojects.last_img read more

These were the top 10 NYC retail leases in August

first_imgClockwise from top left: 35-00 48th Street in Astoria, 558 Broadway, 63 Madison Avenue, and 85 Jay Street in Brooklyn (Credit: Google Maps, Wikipedia, LoopNet, and Williams New York)Apparel and accessories retailers—from luxury watches to sporting goods—secured a big chunk of last month’s top leases. However, the largest lease last month was inked by a fitness club, gyms being a mainstay on these lists.August’s 10 biggest retail leases made public totaled 291,100 square feet, up 113,500 square feet from July’s total of 177,600 square feet. The largest retail lease in August was inked in Dumbo.The total is also more than double the top 10 leases in August 2018.1) Life Time, 85 Jay Street, Dumbo – 77,000 square feetThe fitness club signed a lease for 77,000 square feet of space at Front & York, CIM Group and LIVWRK’s 1.1 million-square-foot development. The location will be the fitness center’s first foray into Brooklyn. Joe Mastromonaco and Fritz Kemerling of Dartmouth Company represented the tenant while CIM Group represented the landlords in-house.ADVERTISEMENT2) Whole Foods, 63 Madison Avenue, Nomad – 60,000 square feetThe Amazon-owned grocery chain signed a lease for 60,000 square feet of space at the base of 63 Madison Avenue, a 15-story property. Peter Duncan, Matt Coudert and Alex Bermingham of George Comfort & Sons represented the landlord in-house.3) Burlington Coat Factory, 35-00 48th Street, Astoria – 40,834 square feetThe discount retailer inked a lease for 40,834 square feet of space previously occupied by Toys “R” Us at 35-00 48th Street. Cliff Simon of CNS Real Estate represented the tenant while Andrew Aberham of Philips International and Jason Lerner of Lerner Properties represented the landlords, Heidenburg Properties and Lerner Properties. BJ’s Wholesale Club is also reported to be moving to the development, also known as Plaza 48.4) Museum of Ice Cream, 558 Broadway, Soho – 25,000 square feetThe Instagram attraction inked a 10-year lease for 25,000 square feet of space at 558 Broadway. The space was previously occupied by H&M. Brandon Charnas and Adam Henick of Current Real Estate Advisors represented the tenant while Shemul family represented the landlord in house.5) Artisanal Brewing Ventures, 94 9th Street, Gowanus – 20,000 square feetThe brewery signed a lease for 20,000 square feet of space at 94 9th Street, where it plans to develop a full-service kitchen and bar in addition to a production brewing system. Andrew Connolly, Jennifer Watson and Peter Whitenack of Newmark Knight Frank represented the tenant, while New York Industrie Capital Partners, which owns the property, brokered the deal in-house.6) New York & Company, 159-10 Jamaica Avenue, Jamaica – 15,115 square feetThe fashion retailer signed a lease for 15,115 square feet of space at 159-10 Jamaica Avenue. Brian Katz of Katz & Associates represented the tenant while Aaron Fleishaker of Mattone Group represented the landlord in house. Other building tenants include Old Navy and Walgreens.7) Blink Fitness, 97-01 Northern Boulevard, East Elmhurst – 15,000 square feetThe gym inked a lease for 15,000 square feet of space at 97-01 Northern Boulevard. Ezra Saff of Retail Zone represented the tenant. The building’s landlord is 361 Henry LLC.8) Modell’s Sporting Goods, 619 West 181st Street, Washington Heights – 14,580 square feetThe sporting goods store signed a 15-year lease for 14,580 square feet of space at 619 West 181st Street. Josh Augenbaum of Augenbaum Realty represented the tenant while Michael Friedman and David Alani of Inline Realty represented the landlord, Rosewood Holding.9) Tourneau, 601 Madison Avenue, Plaza District – 12,050 square feetThe luxury watch retailer signed a short-term lease for 12,050 square feet of space previously leased to Armani at 601 Madison Avenue. The space sat vacant for about a year prior to this lease. Andrew Goldberg and Preston Cannon of CBRE represented the tenant while William Abramson and Matthew Olden of Buchbinder & Warren Realty Group represented the landlord, J-2.10) Lightbridge Academy, 606 West 57th Street, Hell’s Kitchen – 11,491 square feetThe early childhood education center signed a 15-year lease for 11,491 square feet of space at 606 West 57th Street. Brad Schwarz of Lee & Associates NYC represented the tenant while Steven Baker and Daniyel Cohen of Winick Realty Group represented the landlord, TF Cornerstone.Correction: An earlier version of this story misspelled “Industrie Capital Partners’” name.  This content is for subscribers only.Subscribe Nowlast_img read more

New Brexit battle over no deal

first_img“We will make sure that we are not spending money on outcomes that have been effectively ruled out at any stage” — Philip Hammond, chancellor of the exchequerJames Hookham, deputy chief executive of the Freight Transport Association, said he expects the government to row back some of its own contingency planning for no deal in March 2019.“This is the business agenda taking over from the political one,” he said. “There will be a momentum that says: ‘We are going to put all of our very scarce money, effort and time into planning for 2020/21,’ and 2019 drops away by default.”Voices of RemainChancellor Philip Hammond, who has been a leading advocate of a “soft” Brexit in Cabinet, raised eyebrows when he told MPs on the House of Commons European scrutiny committee earlier this month the government would be able to “stand down planning for a no-deal exit in 2019” when it secures transition.“We will make sure that we are not spending money on outcomes that have been effectively ruled out at any stage,” he told MPs.British Chancellor of the Exchequer Philip Hammond | Andy Rain/EPAIn his spring budget statement earlier this month, however, Hammond said the government was still preparing “for all eventualities.” In a written ministerial statement, Chief Secretary to the Treasury Liz Truss outlined which departments would be receiving the biggest slices of a £1.5 billion Brexit preparation funding package for 2018/19. For their colleagues who want to stay closer to the EU after Brexit, however, it makes no sense to prepare for a worst-case scenario that looks unlikely, especially now the EU27 has agreed to a transition period.Brexiteers are concerned that any move to put no-deal preparations on the backburner would undermine Britain’s negotiating position, handing further leverage to Brussels.“The next fight is over no deal,” said one senior U.K. official close to leading Brexiteer Cabinet ministers. “There’s going to be a big push now we’ve got the transition to stop preparing.”Jacob Rees-Mogg, the backbench Conservative MP and leader of the Euroskeptic European Research Group caucus in parliament, said it would be “folly” to stop no-deal preparations. “If we were ready [to walk away with no deal] the EU would not be, as it has made no plans to cut spending in the beneficiary states or raise revenue from the other net contributors. That would leave us in a very strong negotiating position,” he said.Contingency plansWith a little over a year to go before Britain’s departure from the EU, the U.K. government machine is still formally preparing for all eventualities, from a March 2019 cliff-edge if negotiations fail to produce any agreement at all, to a smooth transition toward a “deep and special partnership” between the two sides after Brexit.The lack of clarity means the U.K. government has to pass at least nine separate pieces of Brexit legislation covering everything from immigration to fishing over the next 12 months, just in case a deal cannot be struck on the terms of Britain’s divorce. Monday’s agreement between the U.K. and the European Commission on the terms of a 21-month transition period, however, is a major step on the road to a final deal. At a press conference, U.K. Brexit Secretary David Davis hailed negotiators’ success in “locking down entire chapters” of the final Withdrawal Agreement.U.K. Brexit Secretary David Davis | Jack Taylor/Getty ImagesIf it is ratified by EU leaders when they meet in Brussels at the end of the week, the transition pushes back the point at which Britain exits the EU single market and customs union to December 31, 2020 — but only if a final withdrawal agreement is eventually struck. Throughout the negotiations, both sides have stuck to the mantra that “nothing is agreed until everything is agreed,” leaving everything, in legal terms, up in the air until the last moment.Brexiteers are concerned that any move to put no-deal preparations on the backburner would undermine Britain’s negotiating position, handing further leverage to Brussels.However, those inside government who fiercely oppose the prospect of a no-deal departure believe the transition deal all but eliminates any serious prospect of Britain crashing out of the EU in March 2019 — and the government should start to act as such.One leading pro-European Conservative MP, who did not want to be named, said Brexiteers were “trying to prepare the ground for a walk-away from the negotiations and they are finding the prime minister and No. 10 don’t want to countenance that. She partly called them out on this in her Mansion House speech and really needs to do it again at some point.”Leading figures in business and industry view the transition deal secured this week as a signal to pause plans for a no-deal Brexit in March 2019 — even though it could still fall through. Carolyn Fairbairn, director general of the Confederation of British Industry, said the agreement on transition would give employers “confidence to put their contingency planning on hold.” The Home Office received the most, £395 million, followed by the Department for Environment, Food and Rural Affairs, at £310 million, Her Majesty’s Revenue and Customs, £260 million, and the Department for Business, Energy and Industrial Strategy, £185 million, with other departments receiving smaller amounts.However, it is unclear whether these sums are for no-deal preparations. All of the departments receiving large amounts are ones that would have to enact major projects for any Brexit scenario.The Home Office too — led by Amber Rudd who supported Remain in the referendum — has delayed the introduction of its immigration bill until the end of the year. The department said it was “confident” the new immigration system would be ready in time, but the delay has sparked concern among Brexiteers that the new system will not be in place in time for Britain’s departure should a withdrawal deal hit the rocks. LONDON — To prepare for no deal, or not to prepare for no deal — that is the next Brexit battle in Westminster.After securing agreement with the European Commission Monday for a transition period as the U.K. leaves the EU, senior government officials say Brexiteer Cabinet ministers are now braced for a concerted push from colleagues who favor a “soft” exit for the U.K. government to abandon preparations for a scenario in which Britain crashes out of the bloc.The preparations are crucial, say Brexiteers, because the U.K. needs to be able to continue demonstrating to Brussels that it is serious about walking away from the Brexit talks in order to secure a good deal.last_img read more