Tag: 上海楼凤VR

Wellington baseball team falls to 5-8 with Buhler sweep, Mulvane split

first_img Close Forgot password? Please put in your email: Send me my password! Close message Login This blog post All blog posts Subscribe to this blog post’s comments through… RSS Feed Subscribe via email Subscribe Subscribe to this blog’s comments through… RSS Feed Subscribe via email Subscribe Follow the discussion Comments Logging you in… Close Login to IntenseDebate Or create an account Username or Email: Password: Forgot login? Cancel Login Close WordPress.com Username or Email: Password: Lost your password? Cancel Login Dashboard | Edit profile | Logout Logged in as Admin Options Disable comments for this page Save Settings You are about to flag this comment as being inappropriate. Please explain why you are flagging this comment in the text box below and submit your report. The blog admin will be notified. Thank you for your input. There are no comments posted yet. Be the first one! Post a new comment Enter text right here! Comment as a Guest, or login: Login to IntenseDebate Login to WordPress.com Login to Twitter Go back Tweet this comment Connected as (Logout) Email (optional) Not displayed publicly. Name Email Website (optional) Displayed next to your comments. Not displayed publicly. If you have a website, link to it here. Posting anonymously. Tweet this comment Submit Comment Subscribe to None Replies All new comments Comments by IntenseDebate Enter text right here! Reply as a Guest, or login: Login to IntenseDebate Login to WordPress.com Login to Twitter Go back Tweet this comment Connected as (Logout) Email (optional) Not displayed publicly. Name Email Website (optional) Displayed next to your comments. Not displayed publicly. If you have a website, link to it here. Posting anonymously. Tweet this comment Cancel Submit Comment Subscribe to None Replies All new comments Wellington’s Cade Phelps gets hugged by teammates after hitting a 2RBI walk off double in a game with Mulvane last week.by Tracy McCue, Sumner Newscow — The Wellington boys baseball team finds itself in need of breaking a three-game losing streak after getting swept in Buhler Monday. On Thursday, Wellington split with Mulvane, winning the first game 7-6 before losing the second 11-1 at Sellers Park.The Crusaders are 5-8 with one make-up and six games left on the schedule. The Crusaders return home to host Clearwater Thursday. The doubleheader opening pitch starts at 4 p.m. at Sellers Park.Wellington ran into a buzz saw in Buhler, which is 9-1 for the season having lost only to Circle. Buhler would run-rule the Dukes 12-0 after five innings. The northern Crusaders scored three runs in the second, two runs in the third, and seven runs in the fourth. The southern Crusaders went through four pitchers with Therin Frame attributed with the loss allowing five hits.Julian Jimenez was the lone Duke to get a hit in the first contest.The second game was a little better but not much. Wellington was cursed with five errors. Connor Burnett had an especially good game at the plate with three RBIs on two doubles.Wellington scored two runs in the top of the second but fell behind 8-3 after four after a Buhler six-run fourth inning.The Dukes could never recover thereafter.On Thursday, Wellington would open pull off a thrilling 7-6 victory after going into the final inning of game one against Mulvane down 6-4.In the bottom of the seventh, Jimenez led off with a single, followed by Trey Cary fielder’s choice. Derek Driskell loaded the bases on a walk with no outs. Wellington stalled with two straight outs. but Cade Phelps came in and ripped a double to left-center to bring the two runners home.Trouble with that game, Wellington gave up a one-run lead going into the seventh after committing two errors.Phelps was the winning pitcher throwing six innings, allowing six hits, walking two and striking out three. In game two, Wellington gave up three runs in the first and it went downhill from there, losing 11-1 in a five-inning run rule game. The Crusaders gave up 11 hits and committed three errors.Box scores are as follows:Buhler, game #1Buhler, game #2Mulvane, game #1Mulvane, game #2Follow us on Facebook.Follow us on Twitter.last_img read more

Flow of cerebrospinal fluid found to be key signal for neural stem

first_imgImage from a confocal microscope showing so-called pin-wheel structure of the lateral wall of the lateral ventricle: ENaC-positive adult neural stem cell (red) surrounded by ependymal cells. Source: Helmholtz Zentrum München The ancient Greek aphorism panta rhei means “everything flows”, a phrase used by philosophers to describe the constant flux and interplay between the past and renewal. A recent paper lends this relationship a whole new meaning: a team of researchers headed by Professor Magdalena Götz and their collaborators from the LMU (Prof. Benedikt Grothe) and the Henrich-Heine University Düsseldorf have discovered that the flow of cerebrospinal fluid is a key signal for neural stem cell renewal.“Neural stem cells in the brain can divide and mature into neurons and this process plays important roles in various regions of the brain – including olfactory sense and memory,” explains Magdalena Götz, Director of the Institute for Stem Cell Research at Helmholtz Zentrum München and professor at the Institute for Physiological Genomics at the Biomedical Center of LMU. “These cells are located in what is known as the neurogenic stem cell niche one of which is located at the walls of the lateral ventricles, where they are in contact with circulating cerebrospinal fluid.”Related StoriesSlug serves as ‘command central’ for determining breast stem cell healthAlternate cell growth pathway could open door to new treatments for metastatic cancersCancer stem cells elude the body’s immune cells by deactivating danger detectorThe cerebrospinal fluid fills the brain and its roles are still ill understood. This work highlights the role of this fluid as a key signal – but this time not a chemical but a physical signal. Götz and her team, under the guidance of lead author Dr. David Petrik, discovered that brain stem cells are also influenced by the physical forces of the fluid flow.Channel protein plays a key role“The whole mechanism is controlled by the ENaC molecule,” Petrik explains. This abbreviation stands for epithelial sodium (Na) channel and describes a channel protein on the cell surface through which sodium ions stream into the cell’s interior. “We were able to show in an experimental model that brain stem cells are no longer able to divide in the absence of ENaC. Conversely, a stronger ENaC function promotes cell proliferation.”Further tests showed that the function of ENaC is augmented by shear forces exerted on the cells by the cerebrospinal fluid. The physical stimulation causes the channel protein to open for longer time and allow sodium ions to flow into the cell, thus stimulating division.“The results came as a big surprise, since ENaC had previously only been known for its functions in the kidneys and lungs,” says study leader Götz. She and her team now want to better explore the fast signals mediated by ions in stem cells and clarify the extent to which the findings are also relevant to treatment. After all, pharmacological ENaC blockers are already used clinically to relieve certain types of hypertension. Now it is known that they can also influence stem cells in the brain and thus brain function. Here, too, research is in constant flow: panta rhei … May 21 2018Stem cells in the brain can divide and mature into neurons participating in various brain functions, including memory. In a paper published in the journal ‘Cell Stem Cell’, scientists at Helmholtz Zentrum München and Ludwig-Maximilians-Universität München (LMU) have shown how this works. They found that ion channels play a key role in mediating force signals to the neural stem cells to activate them.center_img Source:https://www.helmholtz-muenchen.de/en/news/latest-news/press-information-news/article/44505/index.html#!prettyPhotolast_img read more