Tag: 上海楼凤LD

Hunters do community work

first_imgThe players have previously done  visits to schools, communities and hospitals in Kokopo and over the weekend, they had their first big community event in Port Moresby.They were involved in the Street kids Christmas Feast helping to feed more than 1,500 settlement kids.The players responded to an invitation and were happy to come out and be part of the community and be involved in supportting community initiatives.Hunters’ assistant coach Nigel Hukula said it is  very important that the Hunters participate in community incentives or networking with the community.Hukula said a lot of the players come from communities and have different backgrounds and walks of life and most of the team’s support comes from the communities.“We try to assist where we can as we have great corporate support from business houses as well as making sure that we give back to the community.“It’s very encouraging and allows us to be part of the community and it shows the children that whatever sport they choose to play, it’s good to give back to the community,” he said.The club is hoping to have many more community outings in the future and will plan certain schedules and places they will visit as part of their long term community service obligation.last_img read more

Ingesting blue dye tablet during colonoscopy aids in detecting difficulttosee polyps

first_img Source:http://www.ddw.org May 22 2018Ingestion of a blue dye tablet during bowel prep for colonoscopy could be a significant advance in the early detection of colorectal cancer (CRC). When used in conjunction with colonoscopy, the blue dye increased adenoma detection rate (ADR) by nearly 9 percent, according to a study scheduled for presentation at Digestive Disease Week® (DDW) 2018.Study implicationsEvery year, nearly 137,000 people are diagnosed with CRC, and more than 50,000 people die from the disease. Yet, the disease is largely preventable with regular screening and is treatable with early detection. The challenge is that polyps are not always detected during screening — many polyps are flat or subtle, making them difficult to identify and remove.”Identification of cancerous and pre-cancerous lesions is of utmost importance to prevent CRC,” said Alessandro Repici, MD, professor of gastroenterology and director of endoscopy at Humanitas University Medical School in Milan, Italy, and a primary investigator of the study. “Our study, which used the highest standard of care, allowed gastroenterologists to better detect and remove difficult-to-see polyps, which has great implications for further preventing this disease.”Study designResearchers studied 1,205 patients scheduled for colonoscopy at 20 centers worldwide, with each patient randomly assigned to one of three groups: patients who received a full dose of the blue dye, oral delayed-release methylene blue, during the normal colonoscopy preparation process; patients who received a placebo during preparation; and a group of patients who received a half dose of the study drug. The third group was not part of the analysis but was included for masking purposes to make it harder for participating physicians to know which patients were in the active group.Study results In patients whose preparation included the full 200 mg dose of the oral delayed-release methylene blue, adenomas, or polyps, and carcinomas were found in 56.3 percent of patients. In the placebo group, which utilized the standard of care, adenomas and carcinomas were identified in 47.8 percent. Both groups were screened with the most up-to-date technology available with monitored withdrawal time and blinded second review to avoid execution bias. More flat and small lesions (less than 5 millimeters) were found in patients who used the full dose of the oral delayed-release methylene blue. Additionally, research showed that with the exception of blue feces and urine discoloration, which were expected effects, less than 6 percent of patients experienced mild adverse effects when taking the tablet.Related StoriesCancer killing capability of lesser-known immune cells identifiedNew drug combinations and dosing schedules improve outlook in advanced colon cancerTrends in colonoscopy rates not aligned with increase in early onset colorectal cancer”While utilizing blue dye to increase ADR is not a new concept, the fact that this technology now comes in tablet form is a major advance,” Michael B. Wallace, MD, MPH, professor of medicine and director of the Digestive Disease Research Program at Mayo Clinic in Jacksonville, Florida, and a primary investigator on the Phase III trial. “Our research shows the oral delayed-release methylene blue provides gastroenterologists with a new means to improve their ADR with no additional inconvenience or safety risks to the patient and no supplemental time required to the endoscopist.”Previously, the blue dye had to be mixed by the providers on site, and then sprayed during the colonoscopy, which could be an imprecise, time-consuming and generally localized process. With the development of the tablet form, the majority of the dye releases in the colon in time for highlighting and detecting mucosal lesions during the colonoscopy.Study investigators added that the use of Methylene Blue MMX or other technologies should never be considered a substitute for good colonoscopy technique.Colorectal cancer screening saves lives. Colonoscopy is the only screening method that can screen for and prevent colorectal cancer. According to a study published in the New England Journal of Medicine, every 1 percent increase in the ADR corresponds to a 3 percent decline in the incidence of CRC and a 5 percent decline in CRC fatalities.last_img read more